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DNA Replication If it were so simple in 1953 , why are we still trying to understand it? |
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Early in vitro Studies - Art Kornberg Scientific Model is to find and isolate the enzyme activity of interest. |
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In vitro replication of DNA - Arthur Kornberg dNTP + Primer + Template --> DNA + nPP'sSummary |
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| In 1959, Arthur Kornberg was awarded
the Nobel
Prize for enzymatic synthesis (replication)
of DNA along with co-recipient Severo Ochoa for RNA synthesis. Note this was three years before Watson, Crick, and Wilkins received the prize for the structure of DNA in 1962. |
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After everyone believes that Kornberg has isolated the DNA replication enzyme, John Cairns isolates a strain of E. coli that completely lacks Kornbergs' enzyme. What does this do to your scientific theories? |
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Text iGenetics by Peter J. Russell
This web site is provided for instruction in Botany and Zoology 342
by Kenneth G. Wilson,
Professor of Botany
Miami University
wilsonkg@muohio.edu
